{"version":"company-facts.v1","source":"https://secwatch.observer","generated_at":"2026-07-11T03:51:15.277065+00:00","company":{"ticker":"LIXT","cik":1335105,"company_name":"LIXTE BIOTECHNOLOGY HOLDINGS, INC."},"pagination":{"limit":100,"returned":33,"next_cursor":null},"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer","counterparties":{"contract_counterparty":[{"display_name":"Orbit Capital Inc.","detail":"equity_purchase","count":2,"first_seen":"2025-12-22T23:59:59+00:00","last_seen":"2026-03-10T23:59:59+00:00","evidence_fact_ids":[29416,110695]},{"display_name":"GlaxoSmithKline LLC and The University of Texas M.D. Anderson Cancer Center","detail":"collaboration","count":1,"first_seen":"2025-12-23T23:59:59+00:00","last_seen":"2025-12-23T23:59:59+00:00","evidence_fact_ids":[108922]},{"display_name":"H. 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The proceeds of the Note will be used (i) to repay in full NOMAD’s outstanding obligations under that certain Loan and Security Agreement, dated as of February 12, 2024, between NOMAD and BPCP Investment Holdings, LP, as successor in interest to Bay Point Capital Partners II, LP, with such portion of the proceeds being disbursed by the Company directly to BPCP Investment Holdings, LP on behalf of NOMAD, and (ii) for working capital and general corporate purposes of NOMAD.","confidence":0.9,"filing_url":"https://secwatch.observer/filing/0001493152-26-029308","anchor_url":"https://secwatch.observer/filing/0001493152-26-029308#claim-12cf45ec981fda20d7fd40f7c204eba1b009e5e5","edgar_index_url":"https://www.sec.gov/Archives/edgar/data/1335105/000149315226029308/0001493152-26-029308-index.htm"},{"fact_type":"material_agreement","fact_key":"957b29d8833e8e93e4db401351986eef19b3f6b0","cik":1335105,"ticker":"LIXT","company_name":"LIXTE BIOTECHNOLOGY HOLDINGS, INC.","filed_at":"2026-06-04T21:01:23+00:00","payload":{"action":"entry","agreement_name":"Purchase Agreement","agreement_type":"equity_purchase","counterparty":"certain accredited investors","effective_date":"2026-06-02","item_codes_triggered":["1.01"],"value_text":"approximately $16.6 million"},"claim":"LIXTE BIOTECHNOLOGY HOLDINGS, INC. entered into Purchase Agreement with certain accredited investors valued at approximately $16.6 million (effective 2026-06-02).","evidence_excerpt":"On June 2, 2026, Lixte Biotechnology Holdings, Inc., a Delaware corporation (the “Company”), entered into a Securities Purchase Agreement (the “Purchase Agreement”) with certain accredited investors named therein (the “Purchasers”), pursuant to which the Company agreed to issue and sell, in a registered direct offering (the “Offering”), 2,366,503 shares (the “Common Shares”) of the Company’s Common Stock, par value $0.0001 per share (the “Common Stock”), and Pre-Funded Warrants (“Pre-Funded Warrants”) to purchase 258,859 shares of Common Stock, at an offering price of $6.31 per share (or $6.30 per Pre-Funded Warrant).","confidence":0.9,"filing_url":"https://secwatch.observer/filing/0001493152-26-027307","anchor_url":"https://secwatch.observer/filing/0001493152-26-027307#claim-957b29d8833e8e93e4db401351986eef19b3f6b0","edgar_index_url":"https://www.sec.gov/Archives/edgar/data/1335105/000149315226027307/0001493152-26-027307-index.htm"},{"fact_type":"executive_change","fact_key":"8f181a2c8a","cik":1335105,"ticker":"LIXT","company_name":"LIXTE BIOTECHNOLOGY HOLDINGS, INC.","filed_at":"2026-06-01T12:55:34+00:00","payload":{"action":"appointed","action_category":"appointment","departure_tone":"not_applicable","effective_date":"2026-05-29","interim":false,"role":"Director","role_category":"director","successor_name":null,"successor_named":false},"claim":"Stuart D. 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(effective 2025-12-16).","evidence_excerpt":"On December 16, 2025, the Company and Orbit Capital Inc., a Cayman Islands Corporation (the “Royalty Holder”) entered into a termination letter (“Termination Letter”), whereby the Company and the Royalty Holder terminated that certain Royalty Agreement dated November 24, 2025 (the “Royalty Agreement”).","confidence":0.9,"filing_url":"https://secwatch.observer/filing/0001493152-25-028850","anchor_url":"https://secwatch.observer/filing/0001493152-25-028850#claim-7c4ec215d87d04d9d6cad6543ff1db37b33515c2","edgar_index_url":"https://www.sec.gov/Archives/edgar/data/1335105/000149315225028850/0001493152-25-028850-index.htm"},{"fact_type":"material_agreement","fact_key":"4494be6210d81f1d6b7496cb983e62be956f2712","cik":1335105,"ticker":"LIXT","company_name":"LIXTE BIOTECHNOLOGY HOLDINGS, INC.","filed_at":"2025-12-22T23:59:59+00:00","payload":{"action":"entry","agreement_name":"Placement Agent 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2025-12-18).","evidence_excerpt":"On December 18, 2025, Lixte Biotechnology Holdings, Inc., a Delaware corporation (the “Company”), entered into a Securities Purchase Agreement (the “Purchase Agreement”) with certain accredited investors named therein (the “Purchasers”), pursuant to which the Company agreed to issue and sell, in a registered direct offering (the “Offering”) 526,342 shares (the “Common Shares”) of the Company’s Common Stock, par value $0.0001 per share (the “Common Stock”), Pre-Funded Warrants (“Pre-Funded Warrants”) to purchase 525,000 shares of Common Stock at an offering price of $4.09 per share (or $4.08999 per Pre-Funded Warrant) and Common Warrants (“Common Warrants”) to purchase 1,051,342 shares of Common Stock at an offering price of $3.96 per 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Certificate of Designations creating Series C Convertible Preferred Stock with 2,700 shares, $1,000 stated value, no dividends, limited voting rights, liquidation preference senior to junior securities, convertible into common stock subject to beneficial ownership limitations (effective 2025-11-24).","evidence_excerpt":"On November 24, 2025, the Company filed a Certificate of Designations of Preferences, Rights and Limitations of Series C Convertible Preferred Stock (the “ Certificate of Designation ”) with the Secretary of State of the State of Delaware.","confidence":0.9,"filing_url":"https://secwatch.observer/filing/0001493152-25-024996","anchor_url":"https://secwatch.observer/filing/0001493152-25-024996#claim-19ffa6c3b964fc7654c4fc24cdb41af927f13412","edgar_index_url":"https://www.sec.gov/Archives/edgar/data/1335105/000149315225024996/0001493152-25-024996-index.htm"},{"fact_type":"ma_transaction","fact_key":"aa73720bdb9a8cfb5ca09a679bf5adb474121e9c","cik":1335105,"ticker":"LIXT","company_name":"LIXTE BIOTECHNOLOGY HOLDINGS, INC.","filed_at":"2025-11-25T23:59:59+00:00","payload":{"action":"acquisition","closing_date":"2025-11-24","consideration_text":"2,700 shares of the Company's Series C Preferred Stock, $1,000 stated value per share; 10.56 Bitcoin and 300 Ethereum; $440,000 in cash; and a royalty agreement","counterparty":"Orbit Capital Inc.","effective_date":"2025-11-24","item_codes_triggered":["2.01"]},"claim":"LIXTE BIOTECHNOLOGY HOLDINGS, INC. completed an acquisition involving Orbit Capital Inc. for 2,700 shares of the Company's Series C Preferred Stock, $1,000 stated value per share; 10.56 Bitcoin and 300 Ethereum; $440,000 in cash; and a royalty agreement (closed 2025-11-24).","evidence_excerpt":"pursuant to a lease agreement. At\nthe closing, the Company agreed to pay the following consideration (the “ Consideration ”) in exchange for the Shares:\n(i) issue to Seller 2,700 shares of the Company’s Series C Preferred Stock, $1,000 stated value per share (the “ Series\nC Preferred Stock ”) having such rights and preferences as set forth in the","confidence":0.9,"filing_url":"https://secwatch.observer/filing/0001493152-25-024996","anchor_url":"https://secwatch.observer/filing/0001493152-25-024996#claim-aa73720bdb9a8cfb5ca09a679bf5adb474121e9c","edgar_index_url":"https://www.sec.gov/Archives/edgar/data/1335105/000149315225024996/0001493152-25-024996-index.htm"},{"fact_type":"executive_change","fact_key":"6ef6226f50","cik":1335105,"ticker":"LIXT","company_name":"LIXTE BIOTECHNOLOGY HOLDINGS, INC.","filed_at":"2025-06-17T23:59:59+00:00","payload":{"action":"resigned as Chairman and Chief Executive Officer","action_category":"role_change","departure_tone":"routine","effective_date":"2025-06-16","interim":false,"role":"President and Chief Scientific Officer","role_category":"president","successor_name":"Geordan Pursglove","successor_named":true},"claim":"Bastiaan van der Baan departed as President and Chief Scientific Officer at LIXTE BIOTECHNOLOGY HOLDINGS, INC..","evidence_excerpt":"Bastiaan van der Baan resigned as Chairman of the Board of Directors and Chief Executive Officer","confidence":0.95,"filing_url":"https://secwatch.observer/filing/0001641172-25-015346","anchor_url":"https://secwatch.observer/filing/0001641172-25-015346#claim-6ef6226f50","edgar_index_url":"https://www.sec.gov/Archives/edgar/data/1335105/000164117225015346/0001641172-25-015346-index.htm"},{"fact_type":"executive_change","fact_key":"8244f3f343","cik":1335105,"ticker":"LIXT","company_name":"LIXTE BIOTECHNOLOGY HOLDINGS, INC.","filed_at":"2025-06-17T23:59:59+00:00","payload":{"action":"appointed","action_category":"appointment","departure_tone":"not_applicable","effective_date":"2025-06-16","interim":false,"role":"Chief Executive Officer and Chairman","role_category":"ceo","successor_name":null,"successor_named":false},"claim":"Geordan Pursglove was appointed as Chief Executive Officer and Chairman at LIXTE BIOTECHNOLOGY HOLDINGS, INC..","evidence_excerpt":"effective June 16, 2025, Geordan Pursglove was appointed as the Company’s Chairman of the Board of Directors and Chief Executive Officer,","confidence":0.95,"filing_url":"https://secwatch.observer/filing/0001641172-25-015346","anchor_url":"https://secwatch.observer/filing/0001641172-25-015346#claim-8244f3f343","edgar_index_url":"https://www.sec.gov/Archives/edgar/data/1335105/000164117225015346/0001641172-25-015346-index.htm"},{"fact_type":"exchange_compliance_notice","fact_key":"ea64dfef1cf4f3560eceb14e420fc85da3a35bec","cik":1335105,"ticker":"LIXT","company_name":"LIXTE BIOTECHNOLOGY HOLDINGS, INC.","filed_at":"2025-04-18T23:59:59+00:00","payload":{"company_response":null,"compliance_status":"extension_granted","cure_deadline":"2025-07-03","deficiency_type":"stockholders_equity","delisting_effective_date":null,"exchange":"nasdaq","hearing_date":null,"immediate_listing_effect":null,"minimum_requirement":null,"notice_date":"2025-04-17","notice_type":"extension_granted","plan_due_date":null,"raw_rule_text":"Listing Rule 5550(b)(1)","reported_value":null,"rule_numbers":["5550(b)(1)"],"rules_cited_in_text":true},"claim":"LIXTE BIOTECHNOLOGY HOLDINGS, INC. received a nasdaq extension granted notice regarding stockholders equity (rules 5550(b)(1)).","evidence_excerpt":"April 17, 2025, the Company received notice that the Nasdaq Hearings Panel (the “Panel”) had granted the Company an extension\nin which to regain compliance with all continued listing rules of the Nasdaq Capital Market. The Panel’s determination follows\na hearing on April 3, 2025, at which the Panel considered the Company’s plan to regain compliance with the Equity Rule. As a result\nof the extension, the Panel granted the Company’s request for continued listing on the Nasdaq Capital Market, provided that the\nCompany demonstrates compliance with the Equity Rule and all other continued listing re","confidence":0.9,"filing_url":"https://secwatch.observer/filing/0001641172-25-005466","anchor_url":"https://secwatch.observer/filing/0001641172-25-005466#claim-ea64dfef1cf4f3560eceb14e420fc85da3a35bec","edgar_index_url":"https://www.sec.gov/Archives/edgar/data/1335105/000164117225005466/0001641172-25-005466-index.htm"},{"fact_type":"exchange_compliance_notice","fact_key":"dd54439e1bbe4a52e76e497643db435d8cc5121b","cik":1335105,"ticker":"LIXT","company_name":"LIXTE BIOTECHNOLOGY HOLDINGS, INC.","filed_at":"2025-02-21T23:59:59+00:00","payload":{"company_response":"intends to timely file an appeal and request a Hearing","compliance_status":"hearing_requested","cure_deadline":null,"deficiency_type":"stockholders_equity","delisting_effective_date":null,"exchange":"nasdaq","hearing_date":null,"immediate_listing_effect":null,"minimum_requirement":"$2,500,000","notice_date":"2025-02-19","notice_type":"delisting_notice","plan_due_date":null,"raw_rule_text":"Listing Rule 5550(b)","reported_value":null,"rule_numbers":["5550(b)"],"rules_cited_in_text":true},"claim":"LIXTE BIOTECHNOLOGY HOLDINGS, INC. received a nasdaq delisting notice notice regarding stockholders equity (rules 5550(b)).","evidence_excerpt":"om the Listing Qualifications Department\n(the “Staff”) of the Nasdaq Stock Market LLC (“Nasdaq”) on August 19, 2024 indicating that the Company was not\nin compliance with the minimum stockholders’ equity requirement of $2,500,000 for continued listing on the Nasdaq Capital Market\nunder Listing Rule 5550(b) (the “Stockholders’ Equity Requirement”). On\nOctober 3, 2024, the Company submitted a plan to the Staff to regain compliance with the Stockholders’ Equity Requirement, which\noutlined the Company’s proposed initiatives to regain compliance by raising equity capital through various registered","confidence":0.9,"filing_url":"https://secwatch.observer/filing/0001493152-25-007865","anchor_url":"https://secwatch.observer/filing/0001493152-25-007865#claim-dd54439e1bbe4a52e76e497643db435d8cc5121b","edgar_index_url":"https://www.sec.gov/Archives/edgar/data/1335105/000149315225007865/0001493152-25-007865-index.htm"},{"fact_type":"executive_change","fact_key":"6406cec9be","cik":1335105,"ticker":"LIXT","company_name":"LIXTE BIOTECHNOLOGY HOLDINGS, INC.","filed_at":"2024-06-05T23:59:59+00:00","payload":{"action":"appointed","action_category":"appointment","departure_tone":"not_applicable","effective_date":null,"interim":false,"role":"Chief Medical Officer","role_category":"other_named_officer","successor_name":null,"successor_named":false},"claim":"Jan Schellens was appointed as Chief Medical Officer at LIXTE BIOTECHNOLOGY HOLDINGS, INC..","evidence_excerpt":"Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangement of Certain Officers.","confidence":0.6,"filing_url":"https://secwatch.observer/filing/0001493152-24-022709","anchor_url":"https://secwatch.observer/filing/0001493152-24-022709#claim-6406cec9be","edgar_index_url":"https://www.sec.gov/Archives/edgar/data/1335105/000149315224022709/0001493152-24-022709-index.htm"},{"fact_type":"executive_change","fact_key":"55bb0d3152","cik":1335105,"ticker":"LIXT","company_name":"LIXTE BIOTECHNOLOGY HOLDINGS, INC.","filed_at":"2024-05-29T23:59:59+00:00","payload":{"action":"elected not to renew","action_category":"departure","departure_tone":"routine","effective_date":"2024-07-31","interim":false,"role":"Chief Medical Officer","role_category":"other_named_officer","successor_name":null,"successor_named":false},"claim":"James Miser departed as Chief Medical Officer at LIXTE BIOTECHNOLOGY HOLDINGS, INC..","evidence_excerpt":"On May 24, 2024, Lixte Biotechnology Holdings, Inc. (the “Company”) provided notice to Dr. James Miser that it has elected not to renew the employment agreement between the Company and Dr. Miser pursuant to which Dr. Miser has served as the Company’s Chief Medical Officer.","confidence":0.95,"filing_url":"https://secwatch.observer/filing/0001493152-24-021837","anchor_url":"https://secwatch.observer/filing/0001493152-24-021837#claim-55bb0d3152","edgar_index_url":"https://www.sec.gov/Archives/edgar/data/1335105/000149315224021837/0001493152-24-021837-index.htm"},{"fact_type":"material_agreement","fact_key":"5aa190283d4d331f993eb039a3818234571c758b","cik":1335105,"ticker":"LIXT","company_name":"LIXTE BIOTECHNOLOGY HOLDINGS, INC.","filed_at":"2024-02-26T23:59:59+00:00","payload":{"action":"entry","agreement_name":"License Agreement","agreement_type":"license","counterparty":"National Institute of Neurological Disorders and Stroke (NINDS) and National Cancer Institute (NCI), each an institute or center of the National Institute of Health (NIH)","effective_date":"2024-02-23","item_codes_triggered":["1.01"],"value_text":"$50,000"},"claim":"LIXTE BIOTECHNOLOGY HOLDINGS, INC. entered into License Agreement with National Institute of Neurological Disorders and Stroke (NINDS) and National Cancer Institute (NCI), each an institute or center of the National Institute of Health (NIH) valued at $50,000 (effective 2024-02-23).","evidence_excerpt":"On February 23, 2024, Lixte Biotechnology Holdings, Inc. (the “Company”) entered into a Patent License Agreement (the “License Agreement”) with the National Institute of Neurological Disorders and Stroke (“NINDS”) and the National Cancer Institute (“NCI”), each an institute or center of the National Institute of Health (“NIH”).","confidence":0.9,"filing_url":"https://secwatch.observer/filing/0001493152-24-007784","anchor_url":"https://secwatch.observer/filing/0001493152-24-007784#claim-5aa190283d4d331f993eb039a3818234571c758b","edgar_index_url":"https://www.sec.gov/Archives/edgar/data/1335105/000149315224007784/0001493152-24-007784-index.htm"},{"fact_type":"shareholder_vote","fact_key":"05fd79450eb3199f6f084db7d46ce15390a5014b","cik":1335105,"ticker":"LIXT","company_name":"LIXTE BIOTECHNOLOGY HOLDINGS, INC.","filed_at":"2023-11-28T23:59:59+00:00","payload":{"item_codes_triggered":["5.07"],"meeting_date":"2023-11-27","outcome":"passed","proposal_text":"Approve amendment to the 2020 Stock Incentive Plan to increase common shares issuable by 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Under Amendment 2, the parties will seek to find synthetic lethal combinations in additional cancer types. Amendment 2 also extends the Collaboration Agreement for an additional two years.","confidence":0.95,"filing_url":"https://secwatch.observer/filing/0001493152-23-037533","anchor_url":"https://secwatch.observer/filing/0001493152-23-037533#claim-806eae9d75c53c6106fb2434009162c611cdddc2","edgar_index_url":"https://www.sec.gov/Archives/edgar/data/1335105/000149315223037533/0001493152-23-037533-index.htm"},{"fact_type":"material_agreement","fact_key":"c518992dcca9dd7e8e84fc099715db367e2945d5","cik":1335105,"ticker":"LIXT","company_name":"LIXTE BIOTECHNOLOGY HOLDINGS, INC.","filed_at":"2023-10-05T23:59:59+00:00","payload":{"action":"termination","agreement_name":"Exclusive License Agreement","agreement_type":"license","counterparty":"H. 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Dr. Kovach will no longer act as the Company’s President and Chief Executive Officer, but will continue as the Company’s Chief Scientific Officer.","confidence":0.95,"filing_url":"https://secwatch.observer/filing/0001493152-23-033825","anchor_url":"https://secwatch.observer/filing/0001493152-23-033825#claim-88deb4bac9","edgar_index_url":"https://www.sec.gov/Archives/edgar/data/1335105/000149315223033825/0001493152-23-033825-index.htm"},{"fact_type":"material_agreement","fact_key":"409b885778d6ddcc752facc7dc45767988d7b1b8","cik":1335105,"ticker":"LIXT","company_name":"LIXTE BIOTECHNOLOGY HOLDINGS, INC.","filed_at":"2023-07-20T23:59:59+00:00","payload":{"action":"entry","agreement_name":"Securities Purchase Agreement","agreement_type":"equity_purchase","counterparty":null,"effective_date":"2023-07-18","item_codes_triggered":["1.01"],"value_text":"approximately $3,500,000"},"claim":"LIXTE BIOTECHNOLOGY HOLDINGS, INC. entered into Securities Purchase Agreement valued at approximately $3,500,000 (effective 2023-07-18).","evidence_excerpt":"On July 18, 2023, Lixte Biotechnology Holdings, Inc., a Delaware corporation (the “Company”), entered into a Securities Purchase Agreement (the “Purchase Agreement”) with the purchaser named therein (the “Purchaser”), pursuant to which the Company agreed to issue and sell, in a registered direct offering (the “Registered Offering”), 583,334 shares (the “Shares”) of the Company’s common stock, par value $0.0001 per share (the “Common Stock”) (or common stock equivalents in lieu thereof), and common warrants to purchase up to 583,334 shares of common stock in a concurrent private placement, at a purchase price of $6.00 per share.","confidence":0.9,"filing_url":"https://secwatch.observer/filing/0001493152-23-025013","anchor_url":"https://secwatch.observer/filing/0001493152-23-025013#claim-409b885778d6ddcc752facc7dc45767988d7b1b8","edgar_index_url":"https://www.sec.gov/Archives/edgar/data/1335105/000149315223025013/0001493152-23-025013-index.htm"},{"fact_type":"governance_change","fact_key":"12917c3030012b849c5c39b16d1caee14999328f","cik":1335105,"ticker":"LIXT","company_name":"LIXTE BIOTECHNOLOGY HOLDINGS, INC.","filed_at":"2023-06-06T23:59:59+00:00","payload":{"change_type":"charter_amendment","effective_date":"2023-06-02","item_codes_triggered":["5.03"],"summary_text":"Filed a Certificate of Amendment to the Certificate of Incorporation to effect a 1-for-10 reverse stock split of common stock, effective June 2, 2023."},"claim":"LIXTE BIOTECHNOLOGY HOLDINGS, INC.: Filed a Certificate of Amendment to the Certificate of Incorporation to effect a 1-for-10 reverse stock split of common stock, effective June 2, 2023 (effective 2023-06-02).","evidence_excerpt":"On June 1, 2023, Lixte Biotechnology Holdings, Inc. 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At the Special Meeting, the Company’s stockholders approved an amendment to the Company’s Certificate of Incorporation to combine the Company’s outstanding shares of common stock into a lesser number of outstanding shares (the “Reverse Stock Split”) at a specific ratio up to a maximum of 1-for-10 split, with the exact ratio to be determined by the Company’s Board of Directors (the “Board”), in its sole discretion. Set forth below are the final voting results for the Reverse Stock Split Proposal: Proposal 1 – Approval of Granting the Board discretionary authority to effectuate the Reverse Stock Split. Stockholders of the Company approved granting the Board authority to effectuate the Reverse Stock Split. 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