secwatch.observer — SEC 8-K summary ====================================== Issuer: VERTEX PHARMACEUTICALS INC / MA (VRTX) CIK: 0000875320 Form: 8-K Filed at: 2021-11-02T23:59:59+00:00 Accession: 0000875320-21-000031 Event type: earnings Sentiment: positive Materiality: 0.85 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Vertex Q3 revenue $1.98B (+29% YoY); raises FY2021 guidance to $7.4-7.5B ------------------------------------------------------------------------ - Product revenues of $1.984B (+29% YoY); GAAP diluted EPS $3.28, Non-GAAP $3.56. - Raised FY2021 product revenue guidance to $7.4-7.5B from prior $7.2-7.4B. - TRIKAFTA/KAFTRIO net revenues $1.556B, up 62% YoY from $960M. - Pipeline: VX-880 T1D positive data (1st patient); VX-147 Phase 2 results Q4; VX-548 data Q1 2022. - CTX001 target enrollment achieved in TDT and SCD trials; regulatory submissions planned late 2022. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/875320/000087532021000031/0000875320-21-000031-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/875320/000087532021000031/vrtx-20211102.htm HTML page: https://secwatch.observer/filing/0000875320-21-000031 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer