secwatch.observer — SEC 8-K summary ====================================== Issuer: VERTEX PHARMACEUTICALS INC / MA (VRTX) CIK: 0000875320 Form: 8-K Filed at: 2022-10-27T23:59:59+00:00 Accession: 0000875320-22-000036 Event type: earnings Sentiment: positive Materiality: 0.80 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Vertex Q3 product revenue $2.33B (+18% YoY); raises FY22 guidance to $8.8-8.9B ------------------------------------------------------------------------------ - Product revenue $2.334B, up 18% from Q3 2021; TRIKAFTA/KAFTRIO contributed $2.011B. - GAAP diluted EPS $3.59; non-GAAP diluted EPS $4.01, up 14% YoY. - Full-year 2022 product revenue guidance raised to $8.8-8.9B from prior $8.6-8.7B. - Initiating global regulatory submissions for exa-cel (sickle cell/beta thalassemia) in 2022; Phase 3 for VX-548 (acute pain) started. - Cash and marketable securities $11.5B as of Sept 30, 2022. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/875320/000087532022000036/0000875320-22-000036-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/875320/000087532022000036/vrtx-20221027.htm HTML page: https://secwatch.observer/filing/0000875320-22-000036 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer