secwatch.observer — SEC 8-K summary ====================================== Issuer: VERTEX PHARMACEUTICALS INC / MA (VRTX) CIK: 0000875320 Form: 8-K Filed at: 2025-05-05T23:59:59+00:00 Accession: 0000875320-25-000171 Event type: earnings Sentiment: neutral Materiality: 0.70 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Vertex Q1 revenue $2.77B (+3% YoY); GAAP net income falls to $646M on $379M impairment; FY guidance raised -------------------------------------------------------------------------------- - Revenue $2.77B, +3% YoY; US revenue +9% to $1.66B, ex-US -5% to $1.11B due to Russia IP violation. - GAAP net income $646M vs $1.1B Q1 2024; includes $379M impairment charge on discontinued VX-264 T1D program. - Non-GAAP net income $1.1B vs $1.2B; combined non-GAAP R&D, AIPR&D and SG&A expenses $1.2B. - Raised FY2025 revenue guidance low end to $11.85B-$12B (from $11.75B-$12B); reiterates expense guidance. - JOURNAVX launch: >20,000 prescriptions filled since March; ~94M lives have covered access. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/875320/000087532025000171/0000875320-25-000171-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/875320/000087532025000171/vrtx-20250505.htm HTML page: https://secwatch.observer/filing/0000875320-25-000171 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer