{"schema_version":"secwatch.filing_event.v1","accession":"0000950170-21-002075","form_type":"8-K","ticker":"CMPX","cik":"0001738021","company_name":"Compass Therapeutics, Inc.","filed_at":"2021-10-08T23:59:59+00:00","discovered_at":"2026-05-14T18:04:13.893695+00:00","generated_at":"2026-06-28T21:56:59.204067+00:00","sec_items":["8.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.6,"calibrated_materiality_score":0.6,"confidence":"high","headline":"Compass Therapeutics reports CTX-009 Phase 1 data: 19% ORR at RP2D in heavily pre-treated tumors","bullets":["CTX-009 monotherapy achieved 19% ORR (3/16) at RP2D (10.0-12.5 mg/kg) and 69% DCR.","Across all doses, ORR was 8% (4 partial responses) and DCR was 62% in heavily pre-treated patients (median 3 prior lines).","Treatment well tolerated; no dose-limiting toxicities; hypertension in 38% (17/45), 7 Grade 3.","94% of colorectal and 58% of gastric patients had prior anti-VEGF therapy (bevacizumab/ramucirumab).","Phase 1b combo and Phase 2 studies underway; Compass holds global rights except S. Korea and China."],"urls":{"canonical":"https://secwatch.observer/filing/0000950170-21-002075","json":"https://secwatch.observer/filing/0000950170-21-002075.json","markdown":"https://secwatch.observer/filing/0000950170-21-002075.md","text":"https://secwatch.observer/filing/0000950170-21-002075.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1738021/000095017021002075/0000950170-21-002075-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1738021/000095017021002075/cmpx-20211008.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-28T21:56:59.204067+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}