secwatch.observer — SEC 8-K summary ====================================== Issuer: Beam Therapeutics Inc. (BEAM) CIK: 0001745999 Form: 8-K Filed at: 2022-02-28T23:59:59+00:00 Accession: 0000950170-22-002162 Event type: earnings Sentiment: positive Materiality: 0.85 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Beam reports $1.2B cash post-Pfizer deal; H2 2022 IND milestones set for SCD programs -------------------------------------------------------------------------------- - Pfizer collaboration: $300M upfront, up to $1.35B milestones for in vivo base editing programs. - Cash $1.2B including Pfizer payment; Q4 net loss $64.7M ($0.95/shr), FY net loss $370.6M ($5.77/shr). - Planned H2 2022 IND submissions: BEAM-101 (SCD Phase 1/2), BEAM-102 (SCD), BEAM-201 (T-ALL/TLL). - IND-enabling studies for BEAM-301 (liver-targeted GSDIa) in 2022; second CAR-T candidate nomination due. - R&D expenses $96.8M Q4 (up from $32.5M), G&A $17.8M Q4 (up from $8.4M) YoY. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1745999/000095017022002162/0000950170-22-002162-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1745999/000095017022002162/beam-20220228.htm HTML page: https://secwatch.observer/filing/0000950170-22-002162 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer