secwatch.observer — SEC 8-K summary ====================================== Issuer: Tango Therapeutics, Inc. (TNGX) CIK: 0001819133 Form: 8-K Filed at: 2022-08-10T23:59:59+00:00 Accession: 0000950170-22-016251 Event type: earnings Sentiment: neutral Materiality: 0.60 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Tango Therapeutics Q2 2022 net loss $24.9M; TNG908 Orphan Drug Designation -------------------------------------------------------------------------- - Cash, cash equivalents and marketable securities $416.4M as of June 30, 2022. - Net loss $24.9M ($0.28/share) vs $4.5M ($0.09) in Q2 2021; R&D expense $23.7M vs $19.1M. - TNG908 Phase 1/2 enrolling MTAP-deleted solid tumors; FDA Orphan Drug Designation for MPNST. - TNG462 (45-fold more potent PRMT5 inhibitor) and TNG260 declared development candidates; IND filings expected 1H 2023. - Added to Russell 2000, 3000 and Microcap indexes in June 2022. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1819133/000095017022016251/0000950170-22-016251-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1819133/000095017022016251/tngx-20220810.htm HTML page: https://secwatch.observer/filing/0000950170-22-016251 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer