{"schema_version":"secwatch.filing_event.v1","accession":"0000950170-22-016625","form_type":"8-K","ticker":"SYBX","cik":"0001527599","company_name":"SYNLOGIC, INC.","filed_at":"2022-08-11T23:59:59+00:00","discovered_at":"2026-05-14T18:03:56.030409+00:00","generated_at":"2026-06-24T00:47:56.429633+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"neutral","materiality_score":0.7,"calibrated_materiality_score":0.7,"confidence":"high","headline":"Synlogic Q2 2022 net loss $15.8M; cash $106.8M funds into 2024; three data readouts in H2 2022","bullets":["Net loss $15.8M ($0.22 per share) vs $14.5M ($0.28) in Q2 2021; revenue $0.2M from Roche IBD collaboration.","Cash, equivalents, and short-term investments $106.8M as of June 30, 2022; projected runway into 2024.","Plan to report Phase 2 PKU data in H2 2022 and start Phase 3 in H1 2023; HCU Phase 1 and EH proof-of-concept data also due H2 2022.","Named SYNB2081 (uric acid-lowering Synthetic Biotic for gout), second candidate from Ginkgo Bioworks partnership.","R&D expenses $12.1M (up from $10.7M) and G&A $4.1M (flat YoY)."],"urls":{"canonical":"https://secwatch.observer/filing/0000950170-22-016625","json":"https://secwatch.observer/filing/0000950170-22-016625.json","markdown":"https://secwatch.observer/filing/0000950170-22-016625.md","text":"https://secwatch.observer/filing/0000950170-22-016625.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1527599/000095017022016625/0000950170-22-016625-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1527599/000095017022016625/sybx-20220811.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-24T00:47:56.429633+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}