secwatch.observer — SEC 8-K summary ====================================== Issuer: Fulcrum Therapeutics, Inc. (FULC) CIK: 0001680581 Form: 8-K Filed at: 2022-08-11T23:59:59+00:00 Accession: 0000950170-22-016633 Event type: other_material Sentiment: neutral Materiality: 0.75 Item codes: 2.02, 2.05, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Fulcrum Therapeutics Q2 net loss $34.1M; cuts 18 jobs, saves $40-50M, cash into mid-2024 -------------------------------------------------------------------------------- - Net loss $34.1M ($0.65 per share) vs $19.6M in Q2 2021; cash $169M as of June 30. - Workforce reduction of 18 positions (~25% of planned headcount) primarily in discovery, research, and G&A. - Expects ~$40-50M operating expense savings fully realized by mid-2024; cash runway extended into mid-2024. - Phase 1b data for FTX-6058 in SCD showed HbF increases up to 6.3%; first patient enrolled in Phase 3 REACH trial for losmapimod in FSHD. - Promoted Mel Hayes to COO and Curt Oltmans to Chief Legal Officer. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1680581/000095017022016633/0000950170-22-016633-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1680581/000095017022016633/fulc-20220811.htm HTML page: https://secwatch.observer/filing/0000950170-22-016633 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer