---
schema_version: "secwatch.filing_event.v1"
accession: "0000950170-22-019311"
form_type: "8-K"
ticker: "ASMB"
cik: "0001426800"
company_name: "ASSEMBLY BIOSCIENCES, INC."
filed_at: "2022-10-05T23:59:59+00:00"
generated_at: "2026-06-23T05:20:23.387687+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.65
calibrated_materiality_score: 0.65
confidence: "high"
source: SEC EDGAR
---

# Assembly Bio CEO John McHutchison to retire Dec 31; Jason Okazaki to succeed as CEO Jan 1, 2023

## Summary
- John G. McHutchison to retire as CEO effective Dec 31, 2022; remains board member and chair of Science & Technology Committee.
- Jason A. Okazaki, current President and COO, appointed President and CEO and board member effective Jan 1, 2023.
- Okazaki joined Assembly Bio in 2020; previously SVP Legal at Gilead; promoted to COO in 2021 and President in 2022.
- Dr. McHutchison led expansion beyond core HBV inhibitors to HDV entry inhibitor, interferon-α receptor agonist, and herpes programs.

## SEC filing metadata
- accession: 0000950170-22-019311
- form_type: 8-K
- ticker: ASMB
- cik: 0001426800
- company_name: ASSEMBLY BIOSCIENCES, INC.
- filed_at: 2022-10-05T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.65
- calibrated_materiality_score: 0.65
- confidence: high
- sec_items: 5.02, 7.01, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1426800/000095017022019311/0000950170-22-019311-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1426800/000095017022019311/asmb-20221005.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0000950170-22-019311
- JSON: https://secwatch.observer/filing/0000950170-22-019311.json
- Plain text: https://secwatch.observer/filing/0000950170-22-019311.txt

## Key facts
- Executive change
  John G. McHutchison changed role as Chief Executive Officer at ASSEMBLY BIOSCIENCES, INC..
  - Action: retire
  - Role: Chief Executive Officer
  source text: John G. McHutchison, A.O., M.D. will retire from his role as Chief Executive Officer of the Company, effective December 31, 2022.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1426800/000095017022019311/0000950170-22-019311-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.