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Graphite Bio announces two abstracts accepted for ASH 2022 annual meeting
LENZ Therapeutics, Inc.
- Abstract #5965 describes beta-globin gene replacement strategy for beta-thalassemia using UltraHDR platform.
- Abstract #3468 (poster) details single-cell RNA sequencing method to assess gene-editing outcomes in sickle cell disease.
- CEO Josh Lehrer notes initial proof-of-concept data for nula-cel (SCD therapy) expected mid-2023.
- Nula-cel is a first-in-human gene correction therapy; FDA granted Fast Track and Orphan Drug designations.
- ASH meeting takes place Dec 10-13, 2022 in New Orleans.