secwatch.observer — SEC 8-K summary ====================================== Issuer: Fulcrum Therapeutics, Inc. (FULC) CIK: 0001680581 Form: 8-K Filed at: 2022-11-08T23:59:59+00:00 Accession: 0000950170-22-022910 Event type: earnings Sentiment: neutral Materiality: 0.70 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Fulcrum Therapeutics Q3 net loss $23.7M; cash $221.8M; selected 12mg dose for FTX-6058 SCD trial -------------------------------------------------------------------------------- - Net loss $23.7M vs $20.7M year ago; collaboration revenue fell to $1.2M from $4.9M due to Acceleron wind-down. - Cash, equivalents, and marketable securities $221.8M; cash runway guidance extended into late 2024. - Completed equity raise of ~$80.8M net proceeds in August 2022. - Selected 12mg as dose for next FTX-6058 Phase 1b cohort in sickle cell disease; enrollment continues. - Appointed Santiago Arroyo as CMO and Jeff Jacobs as CSO; losmapimod Phase 3 REACH trial enrollment ongoing. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1680581/000095017022022910/0000950170-22-022910-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1680581/000095017022022910/fulc-20221108.htm HTML page: https://secwatch.observer/filing/0000950170-22-022910 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer