---
schema_version: "secwatch.filing_event.v1"
accession: "0000950170-22-023214"
form_type: "8-K"
ticker: "ALEC"
cik: "0001653087"
company_name: "Alector, Inc."
filed_at: "2022-11-08T23:59:59+00:00"
generated_at: "2026-06-22T03:51:28.128617+00:00"
event_type: "earnings"
sentiment: "negative"
materiality_score: 0.7
calibrated_materiality_score: 0.7
confidence: "high"
source: SEC EDGAR
---

# Alector Q3 2022 net loss $46.1M, cash $758.3M, pipeline advances

## Summary
- Net loss of $46.1M ($0.56 loss per share); prior-year net income $126.6M ($1.56 EPS).
- Collaboration revenue $14.9M, down from $182.4M YoY due to $173.4M GSK license in 2021.
- Cash, cash equivalents and investments $758.3M; runway through 2024.
- Enrolling Phase 3 INFRONT-3 (latozinemab for FTD-GRN) and Phase 2 INVOKE-2 (AL002 for early AD).
- Initiated Phase 1 for AL044 (MS4A target for Alzheimer’s); IND for AL009 (immuno-oncology) expected Q4 2022.

## SEC filing metadata
- accession: 0000950170-22-023214
- form_type: 8-K
- ticker: ALEC
- cik: 0001653087
- company_name: Alector, Inc.
- filed_at: 2022-11-08T23:59:59+00:00
- event_type: earnings
- sentiment: negative
- materiality_score: 0.7
- calibrated_materiality_score: 0.7
- confidence: high
- sec_items: 2.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1653087/000095017022023214/0000950170-22-023214-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1653087/000095017022023214/alec-20221108.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0000950170-22-023214
- JSON: https://secwatch.observer/filing/0000950170-22-023214.json
- Plain text: https://secwatch.observer/filing/0000950170-22-023214.txt

## Key facts
- Earnings Releases
  Alector, Inc. reported the quarter ended September 30, 2022 results: revenue $14.9 million.
  - Period: the quarter ended September 30, 2022
  - Revenue: $14.9 million
  - Result: reported results
  source text: research pipeline and helps drive business strategy. Third Quarter 2022 Financial Results Revenue. Collaboration revenue for the quarter ended September 30, 2022, was $14.9 million, compared to $182.4 million for the same period in 2021. The decrease of $167.6 mil
  evidence_url: https://www.sec.gov/Archives/edgar/data/1653087/000095017022023214/0000950170-22-023214-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.