secwatch.observer — SEC 8-K summary ====================================== Issuer: Alector, Inc. (ALEC) CIK: 0001653087 Form: 8-K Filed at: 2022-11-08T23:59:59+00:00 Accession: 0000950170-22-023214 Event type: earnings Sentiment: negative Materiality: 0.70 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Alector Q3 2022 net loss $46.1M, cash $758.3M, pipeline advances ---------------------------------------------------------------- - Net loss of $46.1M ($0.56 loss per share); prior-year net income $126.6M ($1.56 EPS). - Collaboration revenue $14.9M, down from $182.4M YoY due to $173.4M GSK license in 2021. - Cash, cash equivalents and investments $758.3M; runway through 2024. - Enrolling Phase 3 INFRONT-3 (latozinemab for FTD-GRN) and Phase 2 INVOKE-2 (AL002 for early AD). - Initiated Phase 1 for AL044 (MS4A target for Alzheimer’s); IND for AL009 (immuno-oncology) expected Q4 2022. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1653087/000095017022023214/0000950170-22-023214-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1653087/000095017022023214/alec-20221108.htm HTML page: https://secwatch.observer/filing/0000950170-22-023214 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer