secwatch.observer — SEC 8-K summary ====================================== Issuer: Lyra Therapeutics, Inc. (LYRA) CIK: 0001327273 Form: 8-K Filed at: 2022-11-08T23:59:59+00:00 Accession: 0000950170-22-023254 Event type: earnings Sentiment: negative Materiality: 0.65 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Lyra Therapeutics Q3 net loss $14.8M; pauses ENLIGHTEN II enrollment for in-house mfg -------------------------------------------------------------------------------- - Net loss of $14.8M for Q3 2022, compared to $11.1M in Q3 2021. - Cash and equivalents $109.6M; expected to fund operations through mid-2024. - ENLIGHTEN I Phase 3 trial on track for enrollment completion mid-2023; ENLIGHTEN II paused, resuming Q3 2023. - BEACON Phase 2 trial of LYR-220 advanced to randomized stage; initial data submitted for 2023 meeting. - R&D expenses rose to $10.0M from $7.1M year-over-year due to clinical trial costs. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1327273/000095017022023254/0000950170-22-023254-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1327273/000095017022023254/lyra-20221108.htm HTML page: https://secwatch.observer/filing/0000950170-22-023254 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer