earnings
confidence high
sentiment neutral
materiality 0.60
Prelude Q3 net loss $30.0M; FDA clears two INDs, halts PRMT5 internal development
Prelude Therapeutics Inc
2022-Q3 EPS reported
-$1.84
- Net loss of $30.0M ($0.63 per share) vs $30.7M ($0.66) in Q3 2021.
- Cash, equivalents & marketable securities $224.0M; runway into Q4 2024.
- FDA cleared INDs for PRT3789 (SMARCA2 degrader) and PRT3645 (brain-penetrant CDK4/6 inhibitor).
- Discontinues internal PRMT5 program (PRT543, PRT811) to focus on higher-potential assets.
- PRT2527 CDK9 Phase 1 dose escalation on track for RP2D by year-end; no dose reduction AEs.