other material
confidence high
sentiment positive
materiality 0.75
Apexigen, Inc.: auditor change — Apexigen reports positive Phase 2 data for sotigalimab in liposarcoma; mPFS 12.45 mo
Apexigen, Inc.
- Sotigalimab + doxorubicin achieved median PFS of 12.45 months in liposarcoma patients vs historical <5 months for doxorubicin alone.
- Apexigen plans to expand LPS cohort by 10 patients to inform potential Phase 3 registration-enabling trial.
- Favorable safety profile observed; data supports further development in first-line liposarcoma.
- Study is investigator-sponsored trial in collaboration with Columbia University (Gary Schwartz, PI).