other material
confidence high
sentiment negative
materiality 0.80
Surrozen pauses SZN-1326 Phase 1 trial due to liver enzyme elevations; Q3 net loss $13.4M
Surrozen, Inc./DE
- Voluntarily paused SZN-1326 Phase 1 SAD trial after grade 3 ALT/AST elevations in 3 subjects; transaminases resolved spontaneously.
- SZN-043 Phase 1 ongoing but with grade 1-2 transaminase elevations; re-evaluating timeline.
- Entered partnership with Boehringer Ingelheim for SZN-413; upfront $12.5M, milestones up to $586.5M plus royalties.
- Q3 2022 cash $78.4M (down from $92.7M in Q2); R&D expense $8.6M, net loss $13.4M.