---
schema_version: "secwatch.filing_event.v1"
accession: "0000950170-22-026384"
form_type: "8-K"
ticker: "ASMB"
cik: "0001426800"
company_name: "ASSEMBLY BIOSCIENCES, INC."
filed_at: "2022-12-12T23:59:59+00:00"
generated_at: "2026-06-21T06:04:43.837941+00:00"
event_type: "leadership"
sentiment: "neutral"
materiality_score: 0.5
calibrated_materiality_score: 0.5
confidence: "high"
source: SEC EDGAR
---

# Assembly Bio finalizes CEO succession; Okazaki takes role Jan 1, 2023; board cuts quorum

## Summary
- Jason Okazaki succeeds John McHutchison as CEO effective Jan 1, 2023; base salary $600K, target bonus 60%.
- Severance: 18 months salary + 1.5x target bonus on change-of-control termination; 12 months salary + prorated bonus on non-CIC.
- Board reduced stockholder meeting quorum from majority to one-third after quorum difficulties in 2021 and 2022.
- Equity award for Okazaki expected in March 2023 as part of annual grants; terms not yet determined.

## SEC filing metadata
- accession: 0000950170-22-026384
- form_type: 8-K
- ticker: ASMB
- cik: 0001426800
- company_name: ASSEMBLY BIOSCIENCES, INC.
- filed_at: 2022-12-12T23:59:59+00:00
- event_type: leadership
- sentiment: neutral
- materiality_score: 0.5
- calibrated_materiality_score: 0.5
- confidence: high
- sec_items: 5.02, 5.03, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1426800/000095017022026384/0000950170-22-026384-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1426800/000095017022026384/asmb-20221206.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0000950170-22-026384
- JSON: https://secwatch.observer/filing/0000950170-22-026384.json
- Plain text: https://secwatch.observer/filing/0000950170-22-026384.txt

## Key facts
- Executive change
  Jason A. Okazaki was appointed as Chief Executive Officer at ASSEMBLY BIOSCIENCES, INC..
  - Action: succeed
  - Role: Chief Executive Officer
  source text: Jason A. Okazaki, the Company's President and Chief Operating Officer, would succeed Dr. McHutchison as Chief Executive Officer, effective January 1, 2023
  evidence_url: https://www.sec.gov/Archives/edgar/data/1426800/000095017022026384/0000950170-22-026384-index.htm
- Executive change
  John G. McHutchison departed as Chief Executive Officer at ASSEMBLY BIOSCIENCES, INC..
  - Action: retire
  - Role: Chief Executive Officer
  source text: John G. McHutchison, A.O., M.D. would retire from his role as Chief Executive Officer effective December 31, 2022
  evidence_url: https://www.sec.gov/Archives/edgar/data/1426800/000095017022026384/0000950170-22-026384-index.htm
- Governance Changes
  ASSEMBLY BIOSCIENCES, INC.: Amended and restated Bylaws reducing stockholder meeting quorum from majority to one-third, deleting list of stockholders requirement, and updating advance notice provisions for universal proxy rules (effective 2022-12-07).
  - Change: bylaw amendment
  - Effective: 2022-12-07
  source text: On December 7, 2022, the Board approved an amendment and restatement of the Company's Amended and Restated Bylaws (the "Amended and Restated Bylaws").
  evidence_url: https://www.sec.gov/Archives/edgar/data/1426800/000095017022026384/0000950170-22-026384-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.