secwatch.observer — SEC 8-K summary ====================================== Issuer: LENZ Therapeutics, Inc. (LENZ) CIK: 0001815776 Form: 8-K Filed at: 2023-02-22T23:59:59+00:00 Accession: 0000950170-23-003808 Event type: other_material Sentiment: negative Materiality: 0.85 Item codes: 2.05, 5.02, 8.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Graphite Bio discontinues sickle cell gene therapy nula-cel, cuts workforce 50%, explores strategic alternatives -------------------------------------------------------------------------------- - Discontinues development of nula-cel for sickle cell disease; exploring external continuation. - Reduces workforce by approximately 50%; expects severance costs of ~$4.9M in Q2 2023. - Chief Business Officer and Chief Scientific Officer to depart in Q2 2023. - Preliminary unaudited cash, equivalents, and marketable securities of ~$283.5M as of Dec 31, 2022. - Will continue early-stage non-genotoxic conditioning program; board approved restructuring. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1815776/000095017023003808/0000950170-23-003808-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1815776/000095017023003808/grph-20230216.htm HTML page: https://secwatch.observer/filing/0000950170-23-003808 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer