secwatch.observer — SEC 8-K summary ====================================== Issuer: Xenon Pharmaceuticals Inc. (XENE) CIK: 0001582313 Form: 8-K Filed at: 2023-03-01T23:59:59+00:00 Accession: 0000950170-23-005549 Event type: earnings Sentiment: neutral Materiality: 0.50 Item codes: 2.02, 7.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Xenon reports FY2022 net loss of $125.4M; cash $720.8M; XEN1101 Phase 3 ongoing ------------------------------------------------------------------------------- - Net loss of $125.4M for FY2022 vs $78.9M in 2021; Q4 net loss $37.4M. - Revenue $9.4M for FY2022 vs $18.4M in 2021; no Q4 revenue. - Cash and marketable securities $720.8M as of Dec 31, 2022; sufficient into 2026. - XEN1101 Phase 3 epilepsy trials (X-TOLE2, X-TOLE3, X-ACKT) enrolling; topline MDD data expected Q3 2023. - Neurocrine partner Phase 2 FOS data expected H2 2023; XEN496 Phase 3 EPIK completion expected 2024. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1582313/000095017023005549/0000950170-23-005549-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1582313/000095017023005549/xene-20230301.htm HTML page: https://secwatch.observer/filing/0000950170-23-005549 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer