{"schema_version":"secwatch.filing_event.v1","accession":"0000950170-23-006240","form_type":"8-K","ticker":"ANNX","cik":"0001528115","company_name":"Annexon, Inc.","filed_at":"2023-03-06T23:59:59+00:00","discovered_at":"2026-05-14T18:03:45.397762+00:00","generated_at":"2026-06-18T11:29:13.828891+00:00","sec_items":["2.02","9.01"],"event_type":"earnings","sentiment":"neutral","materiality_score":0.6,"calibrated_materiality_score":0.6,"confidence":"high","headline":"Annexon reports Q4 2022 net loss of $34.4M; cash runway into 2025; reiterates pipeline milestones","bullets":["Net loss of $34.4M for Q4 2022 ($141.9M full year) vs $37.4M Q4 2021.","Cash and equivalents $242.7M as of Dec 31, 2022; expected to fund operations into 2025.","R&D expenses $28.5M in Q4 2022 ($112.5M full year) vs $27.2M Q4 2021.","Phase 2 trial of ANX007 in geographic atrophy on track for initial data mid-2023.","Phase 1 MAD trial of ANX1502 initiated; proof-of-concept in CAD planned for 2023."],"urls":{"canonical":"https://secwatch.observer/filing/0000950170-23-006240","json":"https://secwatch.observer/filing/0000950170-23-006240.json","markdown":"https://secwatch.observer/filing/0000950170-23-006240.md","text":"https://secwatch.observer/filing/0000950170-23-006240.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1528115/000095017023006240/0000950170-23-006240-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1528115/000095017023006240/annx-20230306.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-18T11:29:13.828891+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[{"claim_id":"2449a401ce8388fb6e9a173083d67409a52c02e6","claim":"Annexon, Inc. reported fourth quarter and the year ended December 31, 2022 results: net income Net loss was $34.4 million for the quarter ended December 31, 2022, and $141.9 million for the year ended December 31, 2.","evidence_excerpt":"On March 6, 2023, Annexon, Inc. (the “Company”) announced certain financial results for the fourth quarter and the year ended December 31, 2022.","evidence_source":"SEC 8-K Item 2.02","evidence_url":"https://www.sec.gov/Archives/edgar/data/1528115/000095017023006240/0000950170-23-006240-index.htm","confidence":0.85,"family_label":"Earnings Releases","details":[{"label":"Period","value":"fourth quarter and the year ended December 31, 2022"},{"label":"Net income","value":"Net loss was $34.4 million for the quarter ended December 31, 2022, and $141.9 million for the year ended December 31, 2"},{"label":"Result","value":"reported results"}],"fact_type":"earnings_release"}],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}