secwatch.observer — SEC 8-K summary ====================================== Issuer: Annexon, Inc. (ANNX) CIK: 0001528115 Form: 8-K Filed at: 2023-03-06T23:59:59+00:00 Accession: 0000950170-23-006240 Event type: earnings Sentiment: neutral Materiality: 0.60 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Annexon reports Q4 2022 net loss of $34.4M; cash runway into 2025; reiterates pipeline milestones -------------------------------------------------------------------------------- - Net loss of $34.4M for Q4 2022 ($141.9M full year) vs $37.4M Q4 2021. - Cash and equivalents $242.7M as of Dec 31, 2022; expected to fund operations into 2025. - R&D expenses $28.5M in Q4 2022 ($112.5M full year) vs $27.2M Q4 2021. - Phase 2 trial of ANX007 in geographic atrophy on track for initial data mid-2023. - Phase 1 MAD trial of ANX1502 initiated; proof-of-concept in CAD planned for 2023. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1528115/000095017023006240/0000950170-23-006240-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1528115/000095017023006240/annx-20230306.htm HTML page: https://secwatch.observer/filing/0000950170-23-006240 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer