secwatch.observer — SEC 8-K summary ====================================== Issuer: Korro Bio, Inc. (KRRO) CIK: 0001703647 Form: 8-K Filed at: 2023-03-10T23:59:59+00:00 Accession: 0000950170-23-007138 Event type: other_material Sentiment: negative Materiality: 0.85 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Frequency Therapeutics discontinues hearing programs, cuts 55% staff after Phase 2b miss, shifts to MS remyelination -------------------------------------------------------------------------------- - FX-322-208 Phase 2b for hearing loss failed primary endpoint; company ends both FX-322 and FX-345 programs. - New focus on MS remyelination program; targets clinical development initiation in first half of 2024. - Restructuring reduces workforce by ~55%, completed by end of April 2023; cash runway extended into 2025. - Q4 2022 net loss $17.4M; full year net loss $81.6M; cash, equivalents & marketable securities $83.1M at Dec 31, 2022. - CEO David Lucchino returned from medical leave on March 1, 2023 and resumed all prior duties. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1703647/000095017023007138/0000950170-23-007138-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1703647/000095017023007138/freq-20230310.htm HTML page: https://secwatch.observer/filing/0000950170-23-007138 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer