earnings
confidence high
sentiment neutral
materiality 0.65
4DMT reports FY22 net loss of $107.5M; cash runway into H1 2025; pipeline advances
4D Molecular Therapeutics, Inc.
- Net loss $107.5M in 2022 (vs $71.3M in 2021); revenue $3.1M (vs $18.0M) due to Roche collaboration end.
- Cash, equivalents & marketable securities $218.5M; expected to fund operations into first half 2025.
- 4D-150 wet AMD interim data: >90% reduction in anti-VEGF injections; dose exploration enrolled, phase 2 dose expansion started Jan 2023. DME IND cleared.
- 4D-710 cystic fibrosis: cohort 2 enrollment completed Feb 2023; interim data planned for Q2 2023 conference.
- 4D-310 Fabry cardiomyopathy: interim cardiac improvements shown; FDA clinical hold response expected Q1 2023.