secwatch.observer — SEC 8-K summary ====================================== Issuer: Nuvalent, Inc. (NUVL) CIK: 0001861560 Form: 8-K Filed at: 2023-03-16T23:59:59+00:00 Accession: 0000950170-23-008282 Event type: earnings Sentiment: neutral Materiality: 0.55 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Nuvalent reports net loss of $81.9M for FY22; cash runway into H2 2025 ---------------------------------------------------------------------- - Cash, cash equivalents and marketable securities $472.2M as of Dec 31, 2022; expected to fund operations into H2 2025. - Net loss of $26.1M in Q4 2022 and $81.9M for full year 2022; R&D expenses $63.7M (FY) vs $35.6M in 2021. - Pipeline progress: NVL-520 Phase 1 data supportive of best-in-class profile in ROS1+ NSCLC; NVL-655 Phase 1 enrolling; NVL-330 (HER2 exon20) nominated as development candidate. - Leadership promotions: Henry Pelish to SVP Drug Discovery; John Soglia to SVP Translational Development. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1861560/000095017023008282/0000950170-23-008282-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1861560/000095017023008282/nuvl-20230316.htm HTML page: https://secwatch.observer/filing/0000950170-23-008282 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer