secwatch.observer — SEC 8-K summary ====================================== Issuer: SPRUCE BIOSCIENCES, INC. (SPRB) CIK: 0001683553 Form: 8-K Filed at: 2023-03-16T23:59:59+00:00 Accession: 0000950170-23-008448 Event type: earnings Sentiment: neutral Materiality: 0.65 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Spruce Biosciences reports FY2022 net loss $46.2M, cash $79.1M; pipeline updates -------------------------------------------------------------------------------- - Net loss $46.2M for FY2022 vs $42.3M in 2021; R&D expenses $35.2M, G&A $12.1M. - Cash, equivalents and investments $79.1M as of Dec 31, 2022; additional $53.6M private placement closed Feb 2023. - CAHmelia-203 in adult classic CAH surpassed 50% enrollment; topline data expected H2 2023. - Strategic partnership with Kaken Pharmaceutical for tildacerfont in Japan; $15M upfront received; cash runway into 1H 2025. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1683553/000095017023008448/0000950170-23-008448-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1683553/000095017023008448/sprb-20230316.htm HTML page: https://secwatch.observer/filing/0000950170-23-008448 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer