secwatch.observer — SEC 8-K summary ====================================== Issuer: Tango Therapeutics, Inc. (TNGX) CIK: 0001819133 Form: 8-K Filed at: 2023-03-27T23:59:59+00:00 Accession: 0000950170-23-009852 Event type: earnings Sentiment: neutral Materiality: 0.70 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Tango Therapeutics reports Q4 2022 net loss $29.1M; TNG462 gets Fast Track; appoints new R&D President -------------------------------------------------------------------------------- - Net loss of $29.1M in Q4 2022 ($0.33/share) vs $22.0M ($0.25) in Q4 2021; FY2022 net loss $108.2M ($1.23) vs $58.2M ($0.94). - Cash of $366.1M at Dec 31, 2022 expected to fund operations into 2025. - FDA granted Fast Track Designation to TNG462, a next-gen MTA-cooperative PRMT5 inhibitor for MTAP-deleted cancers. - Adam Crystal, M.D., Ph.D. appointed President of Research and Development in February 2023. - Upcoming: TNG908 proof-of-mechanism update Q2 2023; IND filings for TNG260 (H1 2023) and TNG348 (mid-2023). Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1819133/000095017023009852/0000950170-23-009852-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1819133/000095017023009852/tngx-20220810.htm HTML page: https://secwatch.observer/filing/0000950170-23-009852 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer