other material
confidence high
sentiment positive
materiality 0.85
Arcellx reports 2022 results; announces Kite collaboration for CART-ddBCMA with $325M upfront
Arcellx, Inc.
- Strategic collaboration with Kite (Gilead): $225M upfront + $100M equity; co-commercialize in US, royalties ex-US.
- Phase 1 expansion data: 100% ORR, 71% CR/sCR in evaluable rrMM patients; no delayed neurotoxicity.
- Pivotal iMMagine-1 trial dosed; Phase 1 ACLX-002 for AML/MDS initiated.
- Cash $254.8M at Dec 31, 2022; plus $325M from Kite/Gilead in Jan 2023; expected to fund through BLA filing H1 2025.
- Net loss $188.7M for FY2022 vs $65.0M in 2021; R&D expenses $149.6M.