secwatch.observer — SEC 8-K summary ====================================== Issuer: Lyra Therapeutics, Inc. (LYRA) CIK: 0001327273 Form: 8-K Filed at: 2023-03-29T23:59:59+00:00 Accession: 0000950170-23-010621 Event type: earnings Sentiment: neutral Materiality: 0.70 Item codes: 2.02, 8.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Lyra Therapeutics reports FY2022 net loss $55.3M; cash $97.9M; ENLIGHTEN I on track for mid-2023 enrollment completion -------------------------------------------------------------------------------- - Net loss for FY2022 $55.3M vs $43.5M in 2021; Q4 net loss $14.2M. - Cash and investments $97.9M as of Dec 31, 2022; sufficient into mid-2024. - ENLIGHTEN I Phase 3 enrollment completion on track for mid-2023; ENLIGHTEN II resume enrollment Q2 2023 (ahead of prior Q3 2023). - BEACON Phase 2 data for LYR-220 expected Q4 2023. - Transitioned manufacturing in-house to prepare for commercial production. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1327273/000095017023010621/0000950170-23-010621-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1327273/000095017023010621/lyra-20230329.htm HTML page: https://secwatch.observer/filing/0000950170-23-010621 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer