secwatch.observer — SEC 8-K summary ====================================== Issuer: Alector, Inc. (ALEC) CIK: 0001653087 Form: 8-K Filed at: 2023-05-04T23:59:59+00:00 Accession: 0000950170-23-017859 Event type: earnings Sentiment: neutral Materiality: 0.65 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Alector Q1 net loss $45.9M, cash $669.3M; on track for latozinemab INFRONT-3 regulatory engagement in mid-2023 -------------------------------------------------------------------------------- - Revenue $16.5M (down $8M YoY); net loss $45.9M ($0.55/share) vs $44.6M ($0.54/share) in Q1 2022. - Cash, equivalents and investments $669.3M; management expects runway through 2025. - On track to discuss INFRONT-3 (latozinemab in FTD-GRN) with regulators mid-2023; data readout early 2025. - Received $17.8M milestone from AbbVie for AL002 LTE enrollment; INVOKE-2 top-line data expected Q4 2024. - 2023 guidance: collaboration revenue $15-25M, R&D expense $225-245M, G&A $60-70M. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1653087/000095017023017859/0000950170-23-017859-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1653087/000095017023017859/alec-20230504.htm HTML page: https://secwatch.observer/filing/0000950170-23-017859 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer