---
schema_version: "secwatch.filing_event.v1"
accession: "0000950170-23-035939"
form_type: "8-K"
ticker: "BMEA"
cik: "0001840439"
company_name: "Biomea Fusion, Inc."
filed_at: "2023-07-31T23:59:59+00:00"
generated_at: "2026-06-12T22:17:11.599181+00:00"
event_type: "earnings"
sentiment: "positive"
materiality_score: 0.75
calibrated_materiality_score: 0.75
confidence: "high"
source: SEC EDGAR
---

# Biomea Fusion Q2 2023: positive diabetes & AML data; net loss widens

## Summary
- Diabetes: in Cohort 3 (100 mg BMF-219 QD), mean HbA1c reduction of 1.49% at Week 12, 62% greater than at end of 4-week dosing.
- 60% of Cohort 3 patients achieved HbA1c ≤7% at Week 12 vs 30% at Week 4; no severe TEAEs off treatment.
- Oncology: 2 complete responses out of 5 relapsed/refractory AML patients carrying menin-dependent mutations at Dose Level 4.
- Cash $223.3M as of June 30, 2023; net loss $24.9M in Q2 2023 vs $17.3M in Q2 2022.
- Initiated Phase I for BMF-500 (COVALENT-103), a third-generation covalent FLT3 inhibitor.

## SEC filing metadata
- accession: 0000950170-23-035939
- form_type: 8-K
- ticker: BMEA
- cik: 0001840439
- company_name: Biomea Fusion, Inc.
- filed_at: 2023-07-31T23:59:59+00:00
- event_type: earnings
- sentiment: positive
- materiality_score: 0.75
- calibrated_materiality_score: 0.75
- confidence: high
- sec_items: 2.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1840439/000095017023035939/0000950170-23-035939-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1840439/000095017023035939/bmea-20230731.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0000950170-23-035939
- JSON: https://secwatch.observer/filing/0000950170-23-035939.json
- Plain text: https://secwatch.observer/filing/0000950170-23-035939.txt

## Key facts
- Earnings Releases
  Biomea Fusion, Inc. reported financial results for the quarter ended June 30, 2023.
  - Period: the quarter ended June 30, 2023
  - Result: reported results
  source text: On July 31, 2023, Biomea Fusion, Inc. issued a press release announcing its financial results for the quarter ended June 30, 2023.
  evidence_url: https://www.sec.gov/Archives/edgar/data/1840439/000095017023035939/0000950170-23-035939-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.