earnings
confidence high
sentiment positive
materiality 0.85
CRISPR Q2 2023 net loss $77.7M; FDA accepts exa-cel BLAs with PDUFA Dec 8 for SCD
CRISPR Therapeutics AG
2023-Q2 EPS reported
-$1.66
revenue$170,000,000
- FDA accepted BLAs for exa-cel: Priority Review for SCD (PDUFA Dec 8, 2023), Standard Review for TDT (Mar 30, 2024).
- Net loss narrowed to $77.7M from $185.8M YoY; collaboration revenue $70M from Vertex milestone.
- Cash and accounts receivable $1,843M; R&D spend $101.6M, down from $123.2M Q2 2022.
- Vertex licensing: $100M upfront received, $70M milestone receivable, up to $230M additional milestones.
- Pipeline: CTX110/130/112/131 trials ongoing; in vivo CTX310 (ANGPTL3) enters clinic in 2023.