other material
confidence high
sentiment positive
materiality 0.80
Aeglea closes Spyre asset acquisition, raises $210M, sells pegzilarginase, reports Q2 loss
Spyre Therapeutics, Inc.
- Acquired Spyre's IBD pipeline (α4β7 and TL1A) for stock; raised $210M gross via Series A preferred private placement.
- Sold pegzilarginase rights to Immedica for $15M upfront + up to $100M milestones; net proceeds to CVR holders.
- Cash and equivalents $236.7M at June 30, including $210M financing; Q2 net loss $217.1M from acquisition-related charges.
- Net loss includes $130.5M acquired IPR&D expense and $58.2M forward contract liability expense.
- Expect SPY001 FIH study in H1 2024; SPY002 FIH study in H2 2024; healthy volunteer data by end-2024 / H1 2025.