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confidence high
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materiality 0.65
aTyr Pharma initiates Phase 2 EFZO-CONNECT study of efzofitimod in SSc-ILD
aTYR PHARMA INC
- EFZO-CONNECT is a randomized, double-blind, placebo-controlled Phase 2 proof-of-concept study in systemic sclerosis-associated ILD.
- Study enrolls 25 patients across multiple US centers; 28-week treatment with monthly IV doses of efzofitimod (270 mg or 450 mg) or placebo.
- Primary objective: evaluate efficacy of efzofitimod on pulmonary, cutaneous, and systemic manifestations in SSc-ILD.