regulatory
confidence high
sentiment neutral
materiality 0.75
Nkarta, Inc. (NKTX): restructuring charge — Nkarta gets FDA IND clearance for NKX019 in LN; cuts workforce 10%, extends cash runway
Nkarta, Inc.
- FDA cleared IND for NKX019 (CAR NK) for lupus nephritis; enrollment starts H1 2024; up to 12 patients.
- RIF of 18 employees (~10% workforce); $1M-$1.5M severance costs in Q4 2023; extends cash runway into 2026.
- Preliminary cash $278.4M as of Sep 30, 2023; cash runway extended one year into 2026.
- NKX019 NHL: new compressed dosing cohort (Days 0,3,7) for LBCL; prior expansion cohorts discontinued.
- Clinical updates in 2024: NKX101 AML H1, NKX019 NHL mid-2024, NKX019 LN in 2024.