other material
confidence high
sentiment neutral
materiality 0.75
Galecto reports 60% response rate in GALLANT-1 part A; halts Part B to focus on liver disease
Damora Therapeutics, Inc.
- Three of five NSCLC patients at 100 mg GB1211 BID plus atezolizumab achieved partial response vs. 22–38% for atezolizumab monotherapy.
- Galecto will not initiate Part B of GALLANT-1, reallocating resources to severe liver diseases as part of strategic alternative process.
- Two severe dose-limiting skin reactions occurred at 200 mg dose; no such reactions at the recommended 100 mg dose level.
- Galecto to supply GB1211 for an investigator-initiated Phase 2 trial at Providence Portland Medical Center expected in early 2024.
- Company plans to explore external options for partnering/funding further oncology activities for GB1211.