{"schema_version":"secwatch.filing_event.v1","accession":"0000950170-23-059042","form_type":"8-K","ticker":"CADL","cik":"0001841387","company_name":"Candel Therapeutics, Inc.","filed_at":"2023-11-06T23:59:59+00:00","discovered_at":"2026-05-14T18:03:30.956956+00:00","generated_at":"2026-06-08T21:28:31.125730+00:00","sec_items":["7.01","8.01","9.01"],"event_type":"other_material","sentiment":"positive","materiality_score":0.5,"calibrated_materiality_score":0.5,"confidence":"high","headline":"Candel presents preclinical data at SITC for enLIGHTEN platform; Alpha-201-macro1 shows enhanced cancer cell killing","bullets":["Preclinical data for enLIGHTEN Discovery Platform presented at SITC 2023 Annual Meeting in San Diego.","Alpha-201-macro1, first experimental agent from platform, targets CD47/SIRPα pathway via local delivery.","enLIGHTEN Advanced Analytics suite predicted multi-gene payload combinations from ICI-treated patient datasets.","Viral chassis Alpha-201 armed with immunostimulatory payloads enhanced PBMC-mediated cancer cell killing in preclinical models.","Data validate in silico prediction of payload combinations using human datasets to de-risk viral immunotherapy development."],"urls":{"canonical":"https://secwatch.observer/filing/0000950170-23-059042","json":"https://secwatch.observer/filing/0000950170-23-059042.json","markdown":"https://secwatch.observer/filing/0000950170-23-059042.md","text":"https://secwatch.observer/filing/0000950170-23-059042.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1841387/000095017023059042/0000950170-23-059042-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1841387/000095017023059042/cadl-20231104.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-06-08T21:28:31.125730+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}