secwatch.observer — SEC 8-K summary ====================================== Issuer: Tyra Biosciences, Inc. (TYRA) CIK: 0001863127 Form: 8-K Filed at: 2023-11-07T23:59:59+00:00 Accession: 0000950170-23-060235 Event type: earnings Sentiment: neutral Materiality: 0.65 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Tyra Biosciences reports Q3 net loss $21.2M; cash $215.7M; advances TYRA-300 and TYRA-200 trials -------------------------------------------------------------------------------- - Q3 2023 net loss $21.2M vs $12.5M YoY; R&D expenses $19.3M (prior $10.9M). - Cash and equivalents $215.7M as of Sept 30, 2023; funds operations for at least two years. - SURF301 Phase 1/2 for TYRA-300 (FGFR3 inhibitor) dose escalation ongoing; preclinical achondroplasia data positive. - TYRA-200 Phase 1 in FGFR2-altered cholangiocarcinoma on track to dose first patient by YE 2023. - FDA granted TYRA-300 Orphan Drug Designation for achondroplasia in July 2023. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1863127/000095017023060235/0000950170-23-060235-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1863127/000095017023060235/tyra-20231107.htm HTML page: https://secwatch.observer/filing/0000950170-23-060235 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer