---
schema_version: "secwatch.filing_event.v1"
accession: "0000950170-24-002304"
form_type: "8-K"
ticker: "PSNL"
cik: "0001527753"
company_name: "Personalis, Inc."
filed_at: "2024-01-05T23:59:59+00:00"
generated_at: "2026-06-07T03:04:41.675204+00:00"
event_type: "earnings"
sentiment: "positive"
materiality_score: 0.7
calibrated_materiality_score: 0.7
confidence: "high"
source: SEC EDGAR
---

# Personalis reports Q4 revenue of $19.7M (+18% YoY); cash runway extended to Q1 2026

## Summary
- Preliminary Q4 revenue $19.7M, up 18% YoY from $16.7M; full-year revenue $73.5M, up 13%.
- Natera revenue in Q4 was $7.1M (vs $8.2M prior year); pharma/enterprise/other revenue $18.7M.
- Cash and short-term investments $114.0M; cash usage reduced to ~$54M in 2023 from $119M.
- Annual cost-cutting reduced expenses by ~$35M; cash runway extended to Q1 2026.
- CEO cites NeXT Personal Dx launch, Tempus partnership, and progress on clinical evidence.

## SEC filing metadata
- accession: 0000950170-24-002304
- form_type: 8-K
- ticker: PSNL
- cik: 0001527753
- company_name: Personalis, Inc.
- filed_at: 2024-01-05T23:59:59+00:00
- event_type: earnings
- sentiment: positive
- materiality_score: 0.7
- calibrated_materiality_score: 0.7
- confidence: high
- sec_items: 2.02, 9.01
- EDGAR index: https://www.sec.gov/Archives/edgar/data/1527753/000095017024002304/0000950170-24-002304-index.htm
- EDGAR primary document: https://www.sec.gov/Archives/edgar/data/1527753/000095017024002304/psnl-20240105.htm

## Machine-readable alternates
- HTML: https://secwatch.observer/filing/0000950170-24-002304
- JSON: https://secwatch.observer/filing/0000950170-24-002304.json
- Plain text: https://secwatch.observer/filing/0000950170-24-002304.txt

## Key facts
- Earnings Releases
  Personalis, Inc. reported the fourth quarter ended December 31, 2023 results: revenue $19.7 million.
  - Period: the fourth quarter ended December 31, 2023
  - Revenue: $19.7 million
  - Result: preliminary results
  source text: Preliminary total company revenue is estimated to be $19.7 million in the fourth quarter of 2023
  evidence_url: https://www.sec.gov/Archives/edgar/data/1527753/000095017024002304/0000950170-24-002304-index.htm
- Earnings Releases
  Personalis, Inc. reported the full year ended December 31, 2023 results: revenue $73.5 million.
  - Period: the full year ended December 31, 2023
  - Revenue: $73.5 million
  - Result: preliminary results
  source text: Preliminary total company revenue is estimated to be $73.5 million in the full year of 2023
  evidence_url: https://www.sec.gov/Archives/edgar/data/1527753/000095017024002304/0000950170-24-002304-index.htm

This AI-assisted summary is a reading aid. Review the linked SEC EDGAR filing before relying on any specific claim.