secwatch.observer — SEC 8-K summary ====================================== Issuer: Beam Therapeutics Inc. (BEAM) CIK: 0001745999 Form: 8-K Filed at: 2024-01-08T23:59:59+00:00 Accession: 0000950170-24-002673 Event type: other_material Sentiment: positive Materiality: 0.70 Item codes: 2.02, 7.01, 8.01, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Beam dosed first SCD patient, submitted CTA for AATD, cash $1.2B into 2027 -------------------------------------------------------------------------- - First patient dosed in BEACON Phase 1/2 trial of BEAM-101 for sickle cell disease; initial data expected H2 2024. - CTA submitted for BEAM-302 in alpha-1 antitrypsin deficiency; trial initiation planned H1 2024. - IND for BEAM-301 in glycogen storage disease 1a on track for H1 2024. - Estimated cash, cash equivalents and marketable securities of $1.2B as of Dec 31, 2023, funding operations into 2027. - BEAM-201 CAR-T trial enrollment ongoing; initial clinical dataset expected H2 2024. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1745999/000095017024002673/0000950170-24-002673-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1745999/000095017024002673/beam-20240108.htm HTML page: https://secwatch.observer/filing/0000950170-24-002673 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer