secwatch.observer — SEC 8-K summary ====================================== Issuer: SPRUCE BIOSCIENCES, INC. (SPRB) CIK: 0001683553 Form: 8-K Filed at: 2024-01-08T23:59:59+00:00 Accession: 0000950170-24-002704 Event type: other_material Sentiment: neutral Materiality: 0.65 Item codes: 2.02, 9.01, 7.01, 8.01 LLM model: deepseek-v4-flash:cloud@v2 Spruce Biosciences provides cash update; adult CAH trials enrollment complete; topline data expected March 2024 -------------------------------------------------------------------------------- - Cash and equivalents ~$96M as of Dec 31, 2023; 41.0M shares outstanding. - CAHmelia-203 (N=96) and CAHptain-205 (N=30) enrollment complete, surpassing targets. - CAHmelia-204 enrollment to finish Jan 2024 (N~98); topline results from CAHmelia-203 and CAHptain-205 expected March 2024. - Baseline characteristics: CAHmelia-203 mean A4 1,149 ng/dL on 27 mg/day GC; CAHmelia-204 mean A4 214 ng/dL on 35 mg/day GC. - Cash runway into first half of 2025. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1683553/000095017024002704/0000950170-24-002704-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1683553/000095017024002704/sprb-20240104.htm HTML page: https://secwatch.observer/filing/0000950170-24-002704 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer