earnings
confidence high
sentiment positive
materiality 0.75
CRISPR Therapeutics 2023: CASGEVY approved in 5 countries; Q4 net income $89.3M
CRISPR Therapeutics AG
2023-FY EPS reported
-$1.94
revenue$371,206,000
- CASGEVY (exa-cel) approved in U.S., EU, Great Britain, Bahrain, KSA for SCD and TDT; ~35,000 patients in U.S. and Europe.
- Q4 net income $89.3M vs net loss $110.6M in Q4 2022; cash $1.7B at year-end, pro-forma >$2.1B after $200M milestone and $280M offering.
- Clinical trials ongoing for next-gen CAR T (CTX112, CTX131) and in vivo programs (CTX310, CTX320); CTX112 trial in SLE planned H1 2024.
- R&D expenses $95.1M in Q4 (down from $103.6M), G&A $16.5M (down from $21.2M); collaboration expense net $20M.
- Vertex paid $170M in 2023 milestones; eligible for additional $160M milestones plus royalties.