secwatch.observer — SEC 8-K summary ====================================== Issuer: Fulcrum Therapeutics, Inc. (FULC) CIK: 0001680581 Form: 8-K Filed at: 2024-02-27T23:59:59+00:00 Accession: 0000950170-24-020615 Event type: earnings Sentiment: neutral Materiality: 0.60 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Fulcrum Therapeutics Q4 2023 net loss $24.8M; Phase 3 REACH data expected Q4 2024 -------------------------------------------------------------------------------- - Net loss $24.8M in Q4 2023 (vs $26.1M); full-year net loss $97.3M (vs $109.9M). - Cash, equivalents, and marketable securities $236.2M; cash runway into 2026. - Phase 3 REACH trial for losmapimod in FSHD on track for topline data in Q4 2024 after enrolling 260 patients. - Phase 1b PIONEER trial for pociredir in SCD restarted; cohorts evaluating 12 mg and 20 mg daily doses. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1680581/000095017024020615/0000950170-24-020615-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1680581/000095017024020615/fulc-20240227.htm HTML page: https://secwatch.observer/filing/0000950170-24-020615 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer