other material
confidence high
sentiment negative
materiality 0.85
Reneo Pharmaceuticals initiates strategic alternatives review after failed trial; Q1 net loss $8.4M
OnKure Therapeutics, Inc.
- STRIDE study of mavodelpar in primary mitochondrial myopathies missed all endpoints in Dec 2023.
- Suspended all mavodelpar development; reduced workforce by ~90% in Dec 2023 and Feb 2024.
- Retained independent financial advisor to explore strategic alternatives, including possible sale.
- Q1 2024 net loss $8.4M ($0.25/share) vs $15.1M ($0.60/share) Q1 2023; cash $82.8M as of Mar 31, 2024.
- R&D expenses fell to $4.9M from $11.0M due to program suspension and cost-cutting.