secwatch.observer — SEC 8-K summary ====================================== Issuer: Repare Therapeutics Inc. (—) CIK: 0001808158 Form: 8-K Filed at: 2024-05-07T23:59:59+00:00 Accession: 0000950170-24-054486 Event type: earnings Sentiment: positive Materiality: 0.75 Item codes: 2.02, 9.01 LLM model: deepseek-v4-flash:cloud@v2 Repare Therapeutics reports Q1 net income $13.2M; FDA agrees on RP2D for lunresertib+camonsertib combination -------------------------------------------------------------------------------- - Net income of $13.2M ($0.30 diluted) vs loss of $34.9M a year ago; revenue $52.4M primarily from $40M Roche milestone. - Cash, equivalents and marketables $237M, sufficient to fund operations at least into mid-2026. - FDA agreed to RP2D for lunresertib 80mg BID + camonsertib 80mg QD; Grade 3 anemia reduced to 25% from 45%. - Regained global rights to camonsertib from Roche; cumulative $182.6M received from Roche under collaboration. - First patient dosed in Phase 1 LIONS trial of PLK4 inhibitor RP-1664; expecting pivotal trial start for lunresertib combo in 2025. Source: EDGAR index: https://www.sec.gov/Archives/edgar/data/1808158/000095017024054486/0000950170-24-054486-index.htm Primary doc: https://www.sec.gov/Archives/edgar/data/1808158/000095017024054486/rptx-20240507.htm HTML page: https://secwatch.observer/filing/0000950170-24-054486 License: Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer