{"schema_version":"secwatch.filing_event.v1","accession":"0000950170-24-095059","form_type":"8-K","ticker":"PRLD","cik":"0001678660","company_name":"Prelude Therapeutics Inc","filed_at":"2024-08-12T23:59:59+00:00","discovered_at":"2026-05-14T18:03:14.075924+00:00","generated_at":"2026-05-31T10:04:38.054748+00:00","sec_items":["2.02","7.01","9.01"],"event_type":"earnings","sentiment":"neutral","materiality_score":0.6,"calibrated_materiality_score":0.6,"confidence":"high","headline":"Prelude Therapeutics Q2 net loss $34.7M; cash $179.8M; clinical milestones for SMARCA2 and CDK9 programs","bullets":["Net loss $34.7M ($0.46/share) vs $30.4M ($0.54/share) in Q2 2023; R&D expense rose to $29.5M from $25.0M.","Cash, equivalents and marketable securities $179.8M at June 30, 2024; runway extended into 2026.","PRT3789 interim Phase 1 data selected for oral presentation at ESMO Congress 2024 (Sept 13).","IND authorized for oral SMARCA2 degrader PRT7732; Phase 1 start expected H2 2024.","Clinical collaboration with Merck to evaluate PRT3789 in combination with KEYTRUDA; Phase 2 start expected Q4 2024."],"urls":{"canonical":"https://secwatch.observer/filing/0000950170-24-095059","json":"https://secwatch.observer/filing/0000950170-24-095059.json","markdown":"https://secwatch.observer/filing/0000950170-24-095059.md","text":"https://secwatch.observer/filing/0000950170-24-095059.txt","edgar_index":"https://www.sec.gov/Archives/edgar/data/1678660/000095017024095059/0000950170-24-095059-index.htm","edgar_primary_document":"https://www.sec.gov/Archives/edgar/data/1678660/000095017024095059/prld-20240812.htm"},"model":{"generated_by":"deepseek-v4-flash:cloud@v2","generated_at":"2026-05-31T10:04:38.054748+00:00"},"review":{"review_status":"machine_generated","human_reviewed":false,"corrected":false,"correction_note":null,"correction_timestamp":null,"superseded_by":null,"related_filings":[]},"source_grounded_claims":[],"license":"Source filings: public domain (SEC EDGAR). Summaries (headline + bullets): CC-BY-4.0; attribute https://secwatch.observer"}