other material
confidence high
sentiment positive
materiality 0.75
SAB Bio completes Phase 1 healthy-volunteer enrollment; SAB-142 shows no serum sickness at 2.5 mg/kg
SAB Biotherapeutics, Inc.
- Phase 1 trial of SAB-142 for type 1 diabetes completed all planned healthy-volunteer cohorts; no serum sickness observed at target 2.5 mg/kg dose.
- Company now enrolling type 1 diabetes patients in the last cohort of the Phase 1 study.
- Topline Phase 1 data readout expected by end of 2024.
- SAB-142 is a first-in-class human anti-thymocyte immunoglobulin with differentiated safety profile compared to rabbit ATG.