other material
confidence high
sentiment positive
materiality 0.80
Assembly Biosciences reports positive interim Phase 1a results for ABI-5366 in recurrent genital herpes
ASSEMBLY BIOSCIENCES, INC.
- ABI-5366 was well-tolerated with favorable safety profile and exposure up to 70 days in healthy participants.
- Half-life of approximately 20 days supports both once-weekly and once-monthly oral dosing schedules.
- Screening for Phase 1b in participants with recurrent genital herpes is now underway.
- Interim Phase 1b results are expected in the first half of 2025.
- Single doses of ABI-5366 surpassed target plasma concentrations for antiviral efficacy.