other material
confidence high
sentiment positive
materiality 0.85
Clearside reports positive ODYSSEY Phase 2b results for CLS-AX in wet AMD; all endpoints met
Clearside Biomedical, Inc.
- ODYSSEY Phase 2b trial of suprachoroidal CLS-AX achieved primary and secondary outcomes; stable BCVA and CSRT through 36 weeks.
- 67% of CLS-AX participants required no additional treatment up to 6 months; 90% up to 4 months, 81% up to 5 months.
- Treatment burden reduced by ~84% compared to average monthly injections prior to screening.
- No ocular or treatment-related SAEs; no endophthalmitis, no retinal vasculitis; well-tolerated safety profile.
- Company plans to advance CLS-AX into Phase 3 development.